Dichloromethane → 4-(6-(Trifluoromethyl)pyridin-2-yl)piperidin-4-ol
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[n:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][cH:19]2)([OH:24])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:32]([Cl:33])[Cl:34].[OH:25][C:26]([C:27]([F:28])([F:29])[F:30])=[O:31]>>[NH:8]1[CH2:9][CH2:10][C:11]([c:14]2[n:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][cH:19]2)([OH:24])[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-213255fa82204195ba414fb087dd421c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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