Potassium Cation → 1-(4-(methylsulfonyl)phenyl)-4-(1-(5-(prop-1-en-2-yl)pyrimidin-2-yl)piperidin-4-yloxy)pyridin-2(1H)-one

HRID 155479

Reaction equation

HRID 155479 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([N:8]2[CH2:9][CH2:10][CH:11]([O:14][c:15]3[cH:16][c:17](=[O:31])[n:18](-[c:21]4[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]4)[cH:19][cH:20]3)[CH2:12][CH2:13]2)[n:6][cH:7]1.[C:32](=[O:33])([O-:34])[O-:35].[CH2:38]=[C:39]([CH3:40])[B:41]([OH:42])[OH:43].[K+:36].[K+:37].[O:44]=[CH:45][N:46]([CH3:47])[CH3:48].[OH2:49]>>[c:2]1([C:39](=[CH2:38])[CH3:40])[cH:3][n:4][c:5]([N:8]2[CH2:9][CH2:10][CH:11]([O:14][c:15]3[cH:16][c:17](=[O:31])[n:18](-[c:21]4[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]4)[cH:19][cH:20]3)[CH2:12][CH2:13]2)[n:6][cH:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 10855372(Prop-1-en-2-yl)boronic acidHCID 252046474-(1-(5-bromopyrimidin-2-yl)piperidin-4-yloxy)-1-(4-(methylsulfonyl)phenyl)pyridin-2(1H)-one

Product 1

HCID 673661321-(4-(methylsulfonyl)phenyl)-4-(1-(5-(prop-1-en-2-yl)pyrimidin-2-yl)piperidin-4-yloxy)pyridin-2(1H)-one

Sources & evidence

ORD record
ord-e9f9da5bb79f4751a9097f5f3417c426
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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