Hydrochloric Acid → 3-(7-Bromo-5-methoxy-2,3-dihydroindol-1-yl)-5-chloro-1-(1-cyclopropylpropyl)pyrazin-2-one

Reaction equation

[Br:17][c:18]1[cH:19][c:20]([O:27][CH3:28])[cH:21][c:22]2[c:26]1[NH:25][CH2:24][CH2:23]2.[Cl:1][c:2]1[c:3](=[O:15])[n:4]([CH:9]([CH2:10][CH3:11])[CH:12]2[CH2:13][CH2:14]2)[cH:5][c:6]([Cl:8])[n:7]1.[ClH:16]>>[c:2]1([N:25]2[CH2:24][CH2:23][c:22]3[cH:21][c:20]([O:27][CH3:28])[cH:19][c:18]([Br:17])[c:26]32)[c:3](=[O:15])[n:4]([CH:9]([CH2:10][CH3:11])[CH:12]2[CH2:13][CH2:14]2)[cH:5][c:6]([Cl:8])[n:7]1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 184528187-Bromo-5-methoxyindoline

HCID 178438347HCID 178438347, compound

Product 1

HCID 184527703-(7-Bromo-5-methoxy-2,3-dihydroindol-1-yl)-5-chloro-1-(1-cyclopropylpropyl)pyrazin-2-one

Sources & evidence

ORD record: ord-4fbfea591ba0486d89ae718681351649
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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