Imidazole → 4-[[3-[Tert-butyl(dimethyl)silyl]oxycyclopentyl]amino]-2-methylsulfanylpyrimidine-5-carbonitrile
Reaction equation
[C:23]([CH3:24])([CH3:25])([CH3:26])[Si:27]([CH3:28])([CH3:29])[Cl:30].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[OH:1][CH:2]1[CH2:3][CH:4]([NH:7][c:8]2[n:9][c:10]([S:16][CH3:17])[n:11][cH:12][c:13]2[C:14]#[N:15])[CH2:5][CH2:6]1.[nH:18]1[cH:19][cH:20][n:21][cH:22]1>>[O:1]([CH:2]1[CH2:3][CH:4]([NH:7][c:8]2[n:9][c:10]([S:16][CH3:17])[n:11][cH:12][c:13]2[C:14]#[N:15])[CH2:5][CH2:6]1)[Si:27]([C:23]([CH3:24])([CH3:25])[CH3:26])([CH3:28])[CH3:29]Participants
5
Sources & evidence
- ORD record
- ord-9d84aa1a41fc4273a3a1e3b87bd7ffc0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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