Ethanol → N,N-bis-(2-hydroxyethyl)-2-fluoro-4-benzyloxyaniline

Reaction equation

[CH2:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[Br:25].[CH3:26][CH2:27][OH:28].[K+:17].[OH-:16].[OH:1][CH2:2][CH2:3][N:4]([c:5]1[c:6]([F:12])[cH:7][c:8]([OH:11])[cH:9][cH:10]1)[CH2:13][CH2:14][OH:15]>>[OH:1][CH2:2][CH2:3][N:4]([c:5]1[c:6]([F:12])[cH:7][c:8]([O:11][CH2:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:9][cH:10]1)[CH2:13][CH2:14][OH:15]

Participants

Reactant 5

HCID 702Ethanol

HCID 813Potassium Cation

HCID 961Hydroxide

HCID 7498Benzyl Bromide

HCID 10822558HCID 10822558, compound

Product 1

HCID 10733374N,N-bis-(2-hydroxyethyl)-2-fluoro-4-benzyloxyaniline

Sources & evidence

ORD record: ord-f4f7a2dd84aa4c1ba1d42169dd93aa97
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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