Bromide ion → 1-(1-Ethyl-6-isopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-8-yl)-propan-1-ol

Reaction equation

[Br-:20].[CH2:21]([CH3:22])[Mg+:23].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][c:6]2[c:11]([c:12]([CH:14]=[O:15])[cH:13]1)[N:10]([CH2:16][CH3:17])[CH2:9][CH2:8][C:7]2([CH3:18])[CH3:19]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][c:6]2[c:11]([c:12]([CH:14]([OH:15])[CH2:21][CH3:22])[cH:13]1)[N:10]([CH2:16][CH3:17])[CH2:9][CH2:8][C:7]2([CH3:18])[CH3:19]

Participants

Reactant 4

HCID 259Bromide ion

HCID 8028Tetrahydrofuran

HCID 227198126-Isopropyl-4,4-dimethyl-1-ethyl-1,2,3,4-tetrahydro-quinoline-8-carbaldehyde

HCID 178461628HCID 178461628, compound

Product 1

HCID 227198191-(1-Ethyl-6-isopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-8-yl)-propan-1-ol

Sources & evidence

ORD record: ord-c6716678f4ca40ceb49d1e939a3242db
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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