Bromide ion → 1-(3-(tert-Butyldimethylsilyloxy)-2,5-difluorophenyl)propan-1-ol
Reaction equation
[Br-:19].[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][c:7]1[c:8]([F:16])[c:9]([CH:10]=[O:11])[cH:12][c:13]([F:15])[cH:14]1)([CH3:17])[CH3:18].[CH2:20]([CH3:21])[Mg+:22].[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][c:7]1[c:8]([F:16])[c:9]([CH:10]([OH:11])[CH2:20][CH3:21])[cH:12][c:13]([F:15])[cH:14]1)([CH3:17])[CH3:18]Participants
5
Sources & evidence
- ORD record
- ord-a9e627b59c88423db1e352c88e008457
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…