Water → 5-Amino-2-methyl-1(2H)-isoquinolinone

Reaction equation

[CH3:1][n:2]1[c:3](=[O:15])[c:4]2[cH:5][cH:6][cH:7][c:8]([N+:12]([O-:13])=[O:14])[c:9]2[cH:10][cH:11]1.[O:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1.[OH2:16].[OH2:17].[Sn:18]([Cl:19])[Cl:20]>>[CH3:1][n:2]1[c:3](=[O:15])[c:4]2[cH:5][cH:6][cH:7][c:8]([NH2:12])[c:9]2[cH:10][cH:11]1

Participants

Reactant 4

HCID 962Water2×

HCID 8028Tetrahydrofuran

HCID 24479Stannous Chloride

HCID 3118562-Methyl-5-nitro-2H-isoquinolin-1-one

Product 1

HCID 122203445-Amino-2-methyl-1(2H)-isoquinolinone

Sources & evidence

ORD record: ord-5cc34ec4994a4b8cab801627237338be
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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