Dimethylformamide → 2-Allyl-2-(4-bromo-phenyl)-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]([CH2:9][n:10]2[c:11]([Cl:18])[n:12][c:13]([N+:15](=[O:16])[O-:17])[cH:14]2)([CH2:19][CH:20]=[CH2:21])[OH:22])[cH:6][cH:7]1.[C:23](=[O:24])([O-:25])[O-:26].[Cs+:27].[Cs+:28].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([CH2:19][CH:20]=[CH2:21])[CH2:9][n:10]3[c:11]([n:12][c:13]([N+:15](=[O:16])[O-:17])[cH:14]3)[O:22]2)[cH:6][cH:7]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 19660Carbonate Ion

HCID 104967Cesium cation2×

HCID 579554882-(4-Bromo-phenyl)-1-(2-chloro-4-nitro-imidazol-1-yl)-pent-4-en-2-ol

Product 1

HCID 442424052-Allyl-2-(4-bromo-phenyl)-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

Sources & evidence

ORD record: ord-6f562eecde13412ab436643d39cbddb4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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