Hydrochloric Acid → HCID 72644366, compound
Reaction equation
[O:1]=[C:2]1[NH:6][C:5](=[O:7])[C:4](=[CH:8][C:9]2[CH:10]=[CH:11][C:12]([O:21][CH3:22])=[C:13]([CH2:15][C:16]([O:18]CC)=[O:17])[CH:14]=2)[S:3]1.Cl>C(O)(=O)C>[O:1]=[C:2]1[NH:6][C:5](=[O:7])[C:4](=[CH:8][C:9]2[CH:10]=[CH:11][C:12]([O:21][CH3:22])=[C:13]([CH2:15][C:16]([OH:18])=[O:17])[CH:14]=2)[S:3]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Ethyl 2-[5-[(2,4-dioxothiazolidin-5-ylidene)methyl]-2-methoxyphenyl]acetate (1.29 g, 4.01 mmol), concentrated hydrochloric acid (20 mL)and acetic acid (20 mL) were mixed and refluxed for 2.5 hours. After allowed to stand for cooling, ice water was added thereto and the precipitated crystals were collected by filtration, washed with water, and then dried to obtain 1.13 g (96%) of title compound as yellow powder.