M-Cresol → HCID 21217664, compound
Reaction equation
[Na].Cl[C:3]1[N:4]=[N:5][C:6]([S:9][CH2:10][CH:11]=[CH2:12])=[CH:7][CH:8]=1.[CH:13]1[C:18]([OH:19])=[CH:17][CH:16]=[CH:15][C:14]=1[CH3:20]>>[CH3:20][C:14]1[CH:13]=[C:18]([CH:17]=[CH:16][CH:15]=1)[O:19][C:3]1[N:4]=[N:5][C:6]([S:9][CH2:10][CH:11]=[CH2:12])=[CH:7][CH:8]=1Participants
4
Conditions
- Temperature
- 100 °C
Procedure
0.23 g(0.01 mol) of metallic sodium was dissolved in 30 ml of dry m-cresol. To the resulting solution was added 1.87 g(0.01 mol) of 3-chloro-6-allylthiopyridazine. The reaction solution was stirred for 5 hours at 100±5° C. and then treated according to the same manner as Example 23 to obtain the title compound as a pale white needle crystal.