Ammonium → 1-Boc-4-methyl-piperidin-4-OL

Reaction equation

[Br-:15].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH3:16][Mg+:17].[CH3:21][CH2:22][O:23][CH2:24][CH3:25].[Cl-:19].[NH4+:20].[OH2:18]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([CH3:16])[CH2:12][CH2:13]1

Participants

Reactant 7

HCID 3283Diethyl Ether

HCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

HCID 178477777HCID 178477777, compound

Product 1

HCID 227308121-Boc-4-methyl-piperidin-4-OL

Sources & evidence

ORD record: ord-2cb0ef75b3574686a89ef05ddf7bc38a
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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