Hydrochloric Acid → HCID 67660708, compound
Reaction equation
[C:1]([CH2:3][CH:4]1[CH2:12][CH:11]2[CH:7]([CH2:8][N:9](C(OC(C)(C)C)=O)[CH2:10]2)[C:6]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)([OH:20])[CH2:5]1)#[N:2].Cl>O1CCOCC1>[C:1]([CH2:3][CH:4]1[CH2:12][CH:11]2[CH:7]([CH2:8][NH:9][CH2:10]2)[C:6]([C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)([OH:20])[CH2:5]1)#[N:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The procedure is as described for Example 13 below, starting from 1.05 g of (3aRS,4RS,6RS,7aSR)-6-cyanomethyl-4-phenyl-2-tert-butyloxycarbonylperhydroisoindol-4-ol and 5 cm3 of a 7N solution of hydrochloric acid in dioxane, and gives 0.63 g of (3aRS,4RS,6RS,7aSR)-6-cyanomethyl-4-phenylperhydroisoindol-4-ol in the form of a thick white foam.