L-Aspartic Acid → L-Aspartic acid, sodium salt (1:2)

HRID 1602564Notes

Reaction equation

HRID 1602564 reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=[O:5].[OH-].[Na+:11].[Na]>O>[NH2:1][C@H:2]([C:7]([O-:9])=[O:8])[CH2:3][C:4]([O-:6])=[O:5].[Na+:11].[Na+:11]

Participants

5

Reactant 3

HCID 5960L-Aspartic Acid2×HCID 14798Sodium HydroxideHCID 5360545Sodium

Product 1

HCID 21806L-Aspartic acid, sodium salt (1:2)

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
150 °C

Procedure

A sample of 50 grams of L-aspartic acid was placed in a 1-liter beaker. To this, 50 ml of distilled water were added and magnetically stirred to form a slurry that contained 0.3755 moles of aspartic acid. Next, 75.1 ml of 10 N NaOH (Fisher Scientific) were slowly pipetted into the solution, thereby adding 0.751 moles of sodium (30.04 grams as NaOH). This solution was not lyophilizible, but was dried first at 120° C. for four hours to form a viscous liquid, then at 150° C. for four more hours which on cooling yielded a white, crystalline mass of disodium aspartate.

Workup

  1. customto form a slurry that
  2. customwas dried first at 120° C. for four hours
  3. customto form a viscous liquid

Sources & evidence

ORD record
ord-164b56152fb04408b4f91a4345c16f67
Source dataset
uspto-grants-1999_11
Patent number
US05981691

Reaction notes

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