Potassium Cation → Methyl 3-fluoro-1-(4-fluorophenyl)-1H-indole-6-carboxylate

HRID 160539

Reaction equation

HRID 160539 reaction equation
[CH3:31][NH:32][CH:33]1[CH2:34][CH2:35][CH2:36][CH2:37][CH:38]1[NH:39][CH3:40].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[Cu:41][I:42].[F:1][c:2]1[cH:3][nH:4][c:5]2[cH:6][c:7]([C:11](=[O:12])[O:13][CH3:14])[cH:8][cH:9][c:10]12.[F:23][c:24]1[cH:25][cH:26][c:27]([I:30])[cH:28][cH:29]1.[K+:20].[K+:21].[K+:22].[P:15]([O-:16])([O-:17])([O-:18])=[O:19]>>[F:1][c:2]1[cH:3][n:4](-[c:27]2[cH:26][cH:25][c:24]([F:23])[cH:29][cH:28]2)[c:5]2[cH:6][c:7]([C:11](=[O:12])[O:13][CH3:14])[cH:8][cH:9][c:10]12

Participants

8

Reactant 7

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 1140TolueneHCID 96054-FluoroiodobenzeneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 5510741-N,2-N-dimethylcyclohexane-1,2-diamineHCID 59625843methyl 3-fluoro-1H-indole-6-carboxylate

Product 1

HCID 59625701Methyl 3-fluoro-1-(4-fluorophenyl)-1H-indole-6-carboxylate

Sources & evidence

ORD record
ord-03dd2c1cfb3e4612be4ac9c8d62e5bab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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