Hydrochloric Acid → 2-(6-Methoxy-2-naphthyl)propionic acid
Reaction equation
C(N)C.[CH3:4][O:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[CH:12]=[C:11]([CH:16]([CH3:20])[C:17]([OH:19])=[O:18])[CH:10]=[CH:9]2.Cl>O>[CH3:4][O:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[CH:12]=[C:11]([CH:16]([CH3:20])[C:17]([OH:19])=[O:18])[CH:10]=[CH:9]2Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
220 g of (+)-2-(6-methoxy-2-naphthyl) propionic acid ethylamine salt was dissolved in 1350 ml of water at 70° C. The obtained completely clear solution was slowly acidified to about pH=5 with 10% w/w hydrochloric acid.
Workup
- customThe obtained completely clear solution
Sources & evidence
- ORD record
- ord-49fca592bea84394b8d539ebfed97057
- Source dataset
- uspto-grants-1989_09
- Patent number
- US04865770
Reaction notes
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