Acetaldehyde → Quindoxin

HRID 1607718

Reaction equation

HRID 1607718 reaction equation
[CH:1]1[CH:9]=[CH:8][C:7]2[C:3](=[N:4][O:5][N+:6]=2[O-:10])[CH:2]=1.[CH:11](=O)[CH3:12]>C(N(CC)CC)C>[CH:9]1[CH:8]=[C:7]2[N:6]([O-:10])[CH:11]=[CH:12][N+:4](=[O:5])[C:3]2=[CH:2][CH:1]=1

Participants

4

Reactant 2

HCID 177AcetaldehydeHCID 68075Benzofuroxan

Product 1

HCID 72073Quindoxin

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

A mixture of benzofuroxan (2.5 g.), acetaldehyde (2.5 ml.) and triethylamine (20 ml.) is allowed to stand at room temperature for 24 hours. The solid material which precipitates is filtered and dried to give product, M.P. 223°-224° C. dec. (MIC against P. vulgaris is 12.5 mcg./ml.).

Workup

  1. customThe solid material which precipitates
  2. filtrationis filtered
  3. customdried
  4. customto give product, M.P. 223°-224° C. dec. (MIC against P. vulgaris is 12.5 mcg./ml.)

Sources & evidence

ORD record
ord-8ce7d3dd4f95463ab3b62df2f02df71b
Source dataset
uspto-grants-1989_09
Patent number
US04866175

Linked notes

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