Sodium Iodide → Tert-butyl[(6-iodohexyl)oxy]dimethylsilane

HRID 1609454

Reaction equation

HRID 1609454 reaction equation
[I-:1].[Na+].[Si:3]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]Cl)([C:6]([CH3:9])([CH3:8])[CH3:7])([CH3:5])[CH3:4]>CC(C)=O>[Si:3]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][I:1])([C:6]([CH3:9])([CH3:8])[CH3:7])([CH3:5])[CH3:4]

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 10083489[(6-Chlorohexyl)oxy](1,1-dimethylethyl)dimethylsilane

Product 1

HCID 13972989Tert-butyl[(6-iodohexyl)oxy]dimethylsilane

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of sodium iodide (13.5 g, 90 mmol) and 1-(tert-butyldimethylsilyloxy)-6-chloro-hexane (Preparation 20) (8.35 g, 22 mmol) in acetone (70 ml) was refluxed overnight. The reaction mixture was cooled to room temperature and filtered. The filtrate was worked-up (hexane) to give the desired compound as yellow oil.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-95e4696a421a497d915996c9261bd306
Source dataset
uspto-grants-1995_03
Patent number
US05401732

Linked notes

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