Benzene → 2-amino-9H-pyrido[2,3-b]indole-3-carboxamide

Reaction equation

[Al+3:26].[Cl-:25].[Cl-:27].[Cl-:28].[NH2:1][c:2]1[c:3]([C:22](=[O:23])[NH2:24])[cH:4][c:5]2[c:6]([n:7]([CH2:14][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)[c:8]3[cH:9][cH:10][cH:11][cH:12][c:13]23)[n:21]1.[cH:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[NH2:1][c:2]1[c:3]([C:22](=[O:23])[NH2:24])[cH:4][c:5]2[c:6]([nH:7][c:8]3[cH:9][cH:10][cH:11][cH:12][c:13]23)[n:21]1

Participants

Reactant 4

HCID 241Benzene

HCID 312Chloride3×

HCID 104727Aluminum Cation

HCID 595136372-amino-9-benzyl-9H-pyrido[2,3-b]indole-3-carboxamide

Product 1

HCID 152709842-amino-9H-pyrido[2,3-b]indole-3-carboxamide

Sources & evidence

ORD record: ord-72b8202760044db9811df1a88e2030a4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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