Diisobutylaluminum hydride → N-(3-{2-[8-(aminomethyl)-1,4-dioxaspiro[4.5]dec-8-yl]-1,3-thiazol-5-yl}-5-methylphenyl)-4-(trifluoromethyl)pyrimidin-2-amine
Reaction equation
[CH2:2]([Al+:3][CH2:4][CH:5]([CH3:6])[CH3:7])[CH:8]([CH3:9])[CH3:10].[CH3:11][c:12]1[cH:13][c:14](-[c:29]2[cH:30][n:31][c:32]([C:34]3([C:44]#[N:45])[CH2:35][CH2:36][C:37]4([O:38][CH2:39][CH2:40][O:41]4)[CH2:42][CH2:43]3)[s:33]2)[cH:15][c:16]([NH:18][c:19]2[n:20][cH:21][cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]2)[cH:17]1.[CH3:46][CH:47]([CH2:48][AlH:49][CH2:50][CH:51]([CH3:52])[CH3:53])[CH3:54].[H-:1]>>[CH3:11][c:12]1[cH:13][c:14](-[c:29]2[cH:30][n:31][c:32]([C:34]3([CH2:44][NH2:45])[CH2:35][CH2:36][C:37]4([O:38][CH2:39][CH2:40][O:41]4)[CH2:42][CH2:43]3)[s:33]2)[cH:15][c:16]([NH:18][c:19]2[n:20][cH:21][cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]2)[cH:17]1
