Benzyl Bromide → 6-benzyl-3-benzyloxycarbonylamino-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid tert-butyl Ester

HRID 161812

Reaction equation

HRID 161812 reaction equation
[Br:58][CH2:59][c:60]1[cH:61][cH:62][cH:63][cH:64][cH:65]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[C:8]1([CH3:29])[CH2:9][CH2:10][c:11]2[n:12]1[c:13](=[O:28])[c:14]([NH:17][C:18](=[O:19])[O:20][CH2:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[cH:15][n:16]2.[CH2:30]([c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1)[O:37][C:38]([NH:39][c:40]1[c:41](=[O:42])[n:43]2[c:54]([n:55][cH:56]1)[CH2:53][CH2:52][CH:44]2[C:45]([O:46][C:47]([CH3:48])([CH3:49])[CH3:50])=[O:51])=[O:57]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[C:8]1([CH2:29][c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH2:9][CH2:10][c:11]2[n:12]1[c:13](=[O:28])[c:14]([NH:17][C:18](=[O:19])[O:20][CH2:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[cH:15][n:16]2

Participants

4

Reactant 3

HCID 7498Benzyl BromideHCID 696008793-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid tert-butyl EsterHCID 76136427tert-butyl 4-oxo-3-(phenylmethoxycarbonylamino)-7,8-dihydro-6H-pyrrolo[1,2-a]pyrimidine-6-carboxylate

Product 1

HCID 696010146-benzyl-3-benzyloxycarbonylamino-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid tert-butyl Ester

Sources & evidence

ORD record
ord-fa6ec56e92104840b608622923cfa4fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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