Benzoyl chloride, 3-bromo- → HCID 25054619, compound
Reaction equation
N1N[N:3]=[N:4][C:5]=1[C:6]1[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=1.[Br:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH:21]=1)[C:16](Cl)=[O:17]>CC1C=CC=CC=1C>[Br:12][C:13]1[CH:14]=[C:15]([C:16]2[O:17][C:5]([C:6]3[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=3)=[N:4][N:3]=2)[CH:19]=[CH:20][CH:21]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
16.8 g (114 mmol) of 3-(2H-tetrazol-5-yl)pyridine) according to Synthesis Example 7 and 25 g (114 mmol) of 3-bromobenzoylchloride were dissolved in 180 mL of o-xylene. The solution was reacted at 150° C. for 8 hours. The obtained reactant was purified under a reduced pressure and washed with methanol, obtaining 30 g (Y=87%) of a white solid.
Workup
- customThe solution was reacted at 150° C. for 8 hours
- customThe obtained reactant was purified under a reduced pressure
- washwashed with methanol
- customobtaining 30 g (Y=87%) of a white solid
Sources & evidence
- ORD record
- ord-853498ba6bf745bf826ae0692858d28a
- Source dataset
- uspto-grants-2014_07
- Patent number
- US08772632B2
Reaction notes
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