Azide → HCID 57517329, compound
Reaction equation
[N-]=[N+]=[N-].[N:4]([C:7]([C:10]1[CH:15]=[CH:14][C:13]([Cl:16])=[C:12]([CH3:17])[CH:11]=1)([CH3:9])[CH3:8])=[N+]=[N-]>CO.O.[Pt](=O)=O>[Cl:16][C:13]1[CH:14]=[CH:15][C:10]([C:7]([NH2:4])([CH3:8])[CH3:9])=[CH:11][C:12]=1[CH3:17]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
A solution of azide INT 21 (4.58 g, 21.84 mmol) in MeOH (100 mL) was hydrogenated at room temperature under atmospheric pressure for 6 hours in the presence of platinum dioxide hydrate (268 mg, 1.1 mmol). The mixture was filtered through Celite and concentrated. The crude was used without further purification.
Workup
- filtrationThe mixture was filtered through Celite
- concentrationconcentrated
- customThe crude was used without further purification
Sources & evidence
- ORD record
- ord-50ccf86980934dd5ace9df5ff3dd3c1c
- Source dataset
- uspto-grants-2014_07
- Patent number
- US08791100B2
Reaction notes
Loading…