Binap, (A+-)- → (5-Chloro-4-dimethoxymethyl-pyridin-2-yl)-[(R)-1-(4-chloro-3-methyl-phenyl)-propyl]-amine

Reaction equation

[CH2:1]([O:3][C:4]([C:6]1[C:11](C)=[CH:10][N:9]=[C:8](Cl)[CH:7]=1)=[O:5])C.[ClH:14].[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([C@H:22]([NH2:25])[CH2:23][CH3:24])=[CH:18][C:17]=1[CH3:26].[CH3:27]C(C)([O-])C.[Na+].C1C=CC(P(C2C(C3C(P(C4C=CC=CC=4)C4C=CC=CC=4)=CC=C4C=3C=CC=C4)=C3C(C=CC=C3)=CC=2)C2C=CC=CC=2)=CC=1>C1(C)C=CC=CC=1.CCOC(C)=O.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd]>[Cl:14][C:11]1[C:6]([CH:4]([O:3][CH3:1])[O:5][CH3:27])=[CH:7][C:8]([NH:25][C@@H:22]([C:19]2[CH:20]=[CH:21][C:16]([Cl:15])=[C:17]([CH3:26])[CH:18]=2)[CH2:23][CH3:24])=[N:9][CH:10]=1