Methyl 4-amino-3-methylbenzoate → Methyl 3-methyl-4-[(1-oxo-4-penten-1-yl)amino]benzoate
Reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[CH3:12]>C1COCC1>[CH3:12][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:2]=1[NH:1][C:6](=[O:7])[CH2:5][CH2:4][CH:3]=[CH2:2])[C:6]([O:8][CH3:9])=[O:7]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
Prepared analogously to Example 46a from methyl 4-amino-3-methyl-benzoate and 4-pentene-1-acid-chloride in THF with TEA.
Sources & evidence
- ORD record
- ord-43cff280b6f14951b2aca18bfc906c43
- Source dataset
- uspto-grants-2014_07
- Patent number
- US08791103B2
Reaction notes
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