3-Bromopyridine → HCID 12011263, compound

HRID 1630845

Reaction equation

HRID 1630845 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1.C([N:15]1[C:23]2[C:18](=[CH:19][C:20]([O:24][CH3:25])=[CH:21][CH:22]=2)[CH:17]=[C:16]1B(O)O)(OC(C)(C)C)=O>>[CH3:25][O:24][C:20]1[CH:19]=[C:18]2[C:23](=[CH:22][CH:21]=1)[NH:15][C:16]([C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1)=[CH:17]2

Participants

3

Reactant 2

HCID 122863-BromopyridineHCID 27947161-Boc-5-methoxyindole-2-boronic acid

Product 1

HCID 12011263HCID 12011263, compound

Procedure

3-Bromopyridine and N-Boc-5-methoxy-indole-2-boronic acid are processed according to the procedure described in Example 91 to give 5-methoxy-2-pyridin-3-yl-1H-indole. HRMS (ESI) m/z 225.1026 [(M+H)+ Calcd for C14H13N2O: 225.1028]

Sources & evidence

ORD record
ord-9f2c294e75134c8dbe4fbe3bafaf9912
Source dataset
uspto-grants-2014_07
Patent number
US08791141B2

Linked notes

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