Methanol → HCID 53749415, compound
Reaction equation
[CH2:1]([N:3]([CH2:6][C:7]1[CH:12]=[CH:11][N:10]=[CH:9][CH:8]=1)[CH2:4][CH3:5])[CH3:2].S(OOS([O-])(=O)=O)([O-])(=O)=O.[NH4+].[NH4+].[CH3:25][OH:26].OS(O)(=O)=O>O>[CH2:1]([N:3]([CH2:6][C:7]1[CH:8]=[CH:9][N:10]=[C:11]([CH2:25][OH:26])[CH:12]=1)[CH2:4][CH3:5])[CH3:2]Participants
6
Reactant 4
Product 1
Reagents, catalysts & solvents 1
Procedure
Treatment of 4-(N,N-diethylaminomethyl)pyridine (2.0 g, 12.20 mmol) with ammonium persulfate (5.56 g, 24.4 g, 2.0 equiv.), methanol (22 ml), water (11 ml) and concentrated H2SO4 (2.76 g, 28.18 mmol, 2.31 equiv.) as described for Cpd #214 gave 0.697 g (29%) of 4-(N,N-diethylaminomethyl)-2-hydroxymethylpyridine.
Sources & evidence
- ORD record
- ord-861ebefcc98f4d0fa5e07b075a2202c4
- Source dataset
- uspto-grants-2000_03
- Patent number
- US06043248
Reaction notes
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