Bicarbonate Ion → 2-Bromo-5-(methoxymethoxy)pyridine

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]([OH:8])[cH:6][n:7]1.[C:15](=[O:16])([OH:17])[O-:18].[Cl:11][CH2:12][O:13][CH3:14].[H-:10].[Na+:19].[Na+:9].[O:20]=[CH:21][N:22]([CH3:23])[CH3:24]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH2:12][O:13][CH3:14])[cH:6][n:7]1

Participants

Reactant 6

HCID 769Bicarbonate Ion

HCID 923Sodium Ion2×

HCID 6228Dimethylformamide

HCID 7864Chloromethyl Methyl Ether

HCID 166653Hydride

HCID 27628652-Bromo-5-hydroxypyridine

Product 1

HCID 574336662-Bromo-5-(methoxymethoxy)pyridine

Sources & evidence

ORD record: ord-94d709fe6d3843558cdad28ea4207951
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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