Water → 1-benzyl-3-(tetrahydro-pyran-4-ylmethyl)-4-(1-triisopropylsilanyl-1H-indazol-5-yl)-piperazin-2-one

HRID 164195

Reaction equation

HRID 164195 reaction equation
[Br:34][CH2:35][CH:36]1[CH2:37][CH2:38][O:39][CH2:40][CH2:41]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9](=[O:33])[CH2:10][N:11]([c:14]2[cH:15][c:16]3[cH:17][n:18][n:19]([Si:23]([CH:24]([CH3:25])[CH3:26])([CH:27]([CH3:28])[CH3:29])[CH:30]([CH3:31])[CH3:32])[c:20]3[cH:21][cH:22]2)[CH2:12][CH2:13]1.[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[OH2:42]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9](=[O:33])[CH:10]([CH2:35][CH:36]2[CH2:37][CH2:38][O:39][CH2:40][CH2:41]2)[N:11]([c:14]2[cH:15][c:16]3[cH:17][n:18][n:19]([Si:23]([CH:24]([CH3:25])[CH3:26])([CH:27]([CH3:28])[CH3:29])[CH:30]([CH3:31])[CH3:32])[c:20]3[cH:21][cH:22]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 962WaterHCID 8028TetrahydrofuranHCID 27732864-(Bromomethyl)oxaneHCID 67335395HCID 67335395, compound

Product 1

HCID 673367111-benzyl-3-(tetrahydro-pyran-4-ylmethyl)-4-(1-triisopropylsilanyl-1H-indazol-5-yl)-piperazin-2-one

Sources & evidence

ORD record
ord-5048bd2ad2324b538c406470bfe5fa91
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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