Sodium Carbonate → HCID 19921162, compound

HRID 1647890

Reaction equation

HRID 1647890 reaction equation
[CH3:1][O:2][C:3]([CH2:5][CH2:6][NH:7][C:8]([C:10]1[CH:25]=[CH:24][C:13]2[N:14]([CH3:23])[C:15]([CH:17]3[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]3)=[N:16][C:12]=2[CH:11]=1)=[O:9])=[O:4].Br.C(S[C:30](=[NH:32])[NH2:31])C.C(=O)([O-])[O-].[Na+].[Na+]>CN(C)C=O>[C:30]([N:20]1[CH2:21][CH2:22][CH:17]([C:15]2[N:14]([CH3:23])[C:13]3[CH:24]=[CH:25][C:10]([C:8]([NH:7][CH2:6][CH2:5][C:3]([O:2][CH3:1])=[O:4])=[O:9])=[CH:11][C:12]=3[N:16]=2)[CH2:18][CH2:19]1)(=[NH:31])[NH2:32]

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 200213S-Ethylisothiuronium bromideHCID 19921265HCID 19921265, compound

Product 1

HCID 19921162HCID 19921162, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared from 5-[(2-methoxycarbonyl-ethyl)-aminocarbonyl]-1-methyl-2-(4-piperidinyl)-benzimidazole and S-ethylisothiourea-hydrobromide by heating to 100° C. for 4 hours in dimethylformamide in the presence of sodium carbonate.

Sources & evidence

ORD record
ord-3203693e9a7b471988dc7a71f97095a1
Source dataset
uspto-grants-1995_07
Patent number
US05434150

Linked notes

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