O-Xylene → HCID 15376513, compound
Reaction equation
[C:1]1([C:7]2[C:8](=O)[O:9][C:10](C)(C)[O:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C=[N:17][C:18]([CH3:26])([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH3:19].[C:27]1(C)C(C)=CC=CC=1>>[CH3:27][C:8]1[O:9][CH2:10][N:17]([C:18]([CH3:26])([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH3:19])[C:12](=[O:11])[C:7]=1[C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1Participants
4
Procedure
Xylene (2 ml) was added to a mixture of 5-phenyl-2,2-dimethyl-2H,4H-1,3-dioxin-4-one (0.82 g) and N-methylene-1-methyl-1-phenylethylamine (0.59 g), and the resulting mixture was heated at reflux for 20 minutes for reaction. The reaction mixture was purified by silica gel chromatography to obtain the captioned compound (0.9 g).
Workup
- temperaturethe resulting mixture was heated