Hydrochloric Acid → HCID 19919494, compound

Reaction equation

C([N:4]1[CH2:9][CH2:8][C:7]2[S:10][C:11]([N+:13]([O-:15])=[O:14])=[CH:12][C:6]=2[CH2:5]1)(=O)C.[ClH:16]>>[ClH:16].[N+:13]([C:11]1[S:10][C:7]2[CH2:8][CH2:9][NH:4][CH2:5][C:6]=2[CH:12]=1)([O-:15])=[O:14]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 199195071-(2-Nitro-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethan-1-one

Product 1

HCID 19919494HCID 19919494, compound

Procedure

2.38 g (10.53 mmole) of 5-acetyl-2-nitro-4,5,6,7-tetrahydrothieno[3,2-c]pyridine [prepared as described in step (b) above] were heated under reflux for 2 hours in 60 ml of 10% w/v aqueous hydrochloric acid. The reaction mixture was then concentrated to dryness by evaporation under reduced pressure, to give 2.19 g of the title compound as brown crystals.

Workup

temperatureunder reflux for 2 hours in 60 ml of 10%
concentrationThe reaction mixture was then concentrated to dryness by evaporation under reduced pressure

Sources & evidence

ORD record: ord-d9926d023fcc4471b3c382e8a46c19b2
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05436242

Reaction notes

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