Bromide ion → Ethyl 2-bromo-1,3-thiazole-4-carboxylate

HRID 164862

Reaction equation

HRID 164862 reaction equation
[Br-:18].[Cu+2:28].[N:19]([O-:20])=[O:21].[NH2:6][c:7]1[s:8][cH:9][c:10]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[n:11]1.[Na+:17].[Na+:22].[OH2:29].[S:1](=[O:2])(=[O:3])([OH:4])[OH:5].[S:23]([O-:24])([O-:25])(=[O:26])=[O:27]>>[c:7]1([Br:18])[s:8][cH:9][c:10]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[n:11]1

Participants

9

Reactant 8

HCID 259Bromide ionHCID 923Sodium ion2×HCID 946NitriteHCID 962WaterHCID 1117Sulfate IonHCID 1118Sulfuric AcidHCID 27099Cupric cationHCID 73216Ethyl 2-aminothiazole-4-carboxylate

Product 1

HCID 353965Ethyl 2-bromo-1,3-thiazole-4-carboxylate

Sources & evidence

ORD record
ord-7c351dd9977742888cdbea8b6a9557b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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