Oxalyl chloride → (+)-cis-3-(2,2-Dibromoethenyl)-2,2-dimethylcyclopropanecarbonyl chloride
Reaction equation
[Br:1][C:2]([Br:12])=[CH:3][C@@H:4]1[C@H:6]([C:7](O)=[O:8])[C:5]1([CH3:11])[CH3:10].C(Cl)(=O)C([Cl:16])=O>C1(C)C=CC=CC=1>[Br:1][C:2]([Br:12])=[CH:3][C@@H:4]1[C@H:6]([C:7]([Cl:16])=[O:8])[C:5]1([CH3:11])[CH3:10]Participants
4
Procedure
In a manner similar to Example 13A, the reaction of 13.0 g (0.0436 mole) of (±)-cis-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylic acid, 50 ml of toluene, and 11.1 g (0.0873 mole) of oxalyl chloride gave 7.0 g of (±)-cis-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarbonyl chloride. The nmr spectrum was consistent with the proposed structure.
Sources & evidence
- ORD record
- ord-65db55c771c6413b9906890ea3b9bdc4
- Source dataset
- uspto-grants-1983_11
- Patent number
- US04417078
Reaction notes
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