Dimethyl Sulfoxide → Cyano-(2-methylthio-pyrimidin-4-yl)-acetic acid tert-butyl ester

HRID 165195

Reaction equation

HRID 165195 reaction equation
[C:3](#[N:4])[CH2:5][C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12].[CH3:24][S:25]([CH3:26])=[O:27].[Cl:15][c:16]1[n:17][c:18]([S:22][CH3:23])[n:19][cH:20][cH:21]1.[H-:1].[H:13][H:14].[Na+:2]>>[C:3](#[N:4])[CH:5]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[c:16]1[n:17][c:18]([S:22][CH3:23])[n:19][cH:20][cH:21]1

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 923Sodium ionHCID 70693tert-Butyl cyanoacetateHCID 971134-Chloro-2-methylthiopyrimidineHCID 166653HydrideHCID 178418361HCID 178418361, compound

Product 1

HCID 51034226Cyano-(2-methylthio-pyrimidin-4-yl)-acetic acid tert-butyl ester

Sources & evidence

ORD record
ord-3d2d53963fd046cb906e0792d7696cbc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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