Water → 1,3-Dihydro-3-methyl-3-(5-pyrimidinylmethyl)-2H-indol-2-one

HRID 165778

Reaction equation

HRID 165778 reaction equation
[CH2:18]([Li:19])[CH2:20][CH2:21][CH3:22].[CH3:12][NH:13][CH2:14][CH2:15][NH:16][CH3:17].[CH3:1][CH:2]1[C:3](=[O:4])[NH:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]21.[CH3:23][c:24]1[cH:25][cH:26][c:27]([S:28]([O:29][CH2:34][c:35]2[cH:36][n:37][cH:38][n:39][cH:40]2)(=[O:30])=[O:31])[cH:32][cH:33]1.[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[OH2:46]>>[CH3:1][C:2]1([CH2:34][c:35]2[cH:36][n:37][cH:38][n:39][cH:40]2)[C:3](=[O:4])[NH:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]21

Participants

7

Reactant 6

HCID 962WaterHCID 8028TetrahydrofuranHCID 8070N,N'-DimethylethylenediamineHCID 1509233-MethyloxindoleHCID 86644145HCID 86644145, compoundHCID 178418339Butyllithium

Product 1

HCID 594437541,3-Dihydro-3-methyl-3-(5-pyrimidinylmethyl)-2H-indol-2-one

Sources & evidence

ORD record
ord-95b9d7b26bd64ebd9239b7f6e534868f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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