2-Propenoic acid, 3-phenyl- → beta-(2'-Chloro-4-biphenylyl)propionic acid

HRID 1659066Notes

Reaction equation

HRID 1659066 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:18]=[CH:17][C:11]([CH:12]=[CH:13][C:14]([OH:16])=[O:15])=[CH:10][CH:9]=1.C(O)(=O)C=CC1C=CC=CC=1>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:18]=[CH:17][C:11]([CH2:12][CH2:13][C:14]([OH:16])=[O:15])=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 87842-Propenoic acid, 3-phenyl-HCID 54534814p-(2-Chlorophenyl)cinnamic acid

Product 1

HCID 1394276beta-(2'-Chloro-4-biphenylyl)propionic acid

Procedure

when p-(2-chlorophenyl)cinnamic acid is replaced by the cinnamic acid compounds of Table II, Example 1 then the corresponding propionic acid is prepared.

Sources & evidence

ORD record
ord-f945cf3631f841dcaf308e55e8780dc3
Source dataset
uspto-grants-1976_06
Patent number
US03966801

Reaction notes

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