Diethanolamine → HCID 86738180, compound
Reaction equation
[P:1]([C:5]([NH:7][NH2:8])=[O:6])([OH:4])([OH:3])=[O:2].N(CCO)[CH2:10][CH2:11][OH:12]>O>[NH4+:7].[CH2:11]([OH:12])[CH3:10].[CH2:11]([OH:12])[CH3:10].[P:1]([C:5]([NH:7][NH2:8])=[O:6])([OH:4])([OH:3])=[O:2]Participants
5
Reactant 2
Product 2
Reagents, catalysts & solvents 1
Procedure
4.4 parts by weight of phosphonoformic acid hydrazide are run in 20 parts by volume of water and neutralised by a 2 molar solution of diethanol amine in water. The resulting solution is evaporated, the evaporation residue is triturated with a mixture of ethanol and methanol (90 parts by volume plus 10 parts by volume) and the crystals are isolated 11 parts by weight of diethanol ammonium salt of phosphonoformic acid hydrazide are obtained (yield 100%).
Workup
- customThe resulting solution is evaporated
- customthe evaporation residue is triturated with a mixture of ethanol and methanol (90 parts by volume plus 10 parts by volume)
Sources & evidence
- ORD record
- ord-416de0ef11e446898d4b2d051140886b
- Source dataset
- uspto-grants-1981_12
- Patent number
- US04308263
Reaction notes
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