1-Bromo-4-fluorobenzene → (4-Fluoro-phenyl)-[1-(2'-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-methanone
Reaction equation
CON(C)[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:12]=[C:13]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[O:23][CH3:24])[CH:14]=[CH:15][CH:16]=2)[CH:10]=1)=[O:5].Br[C:27]1[CH:32]=[CH:31][C:30]([F:33])=[CH:29][CH:28]=1>>[F:33][C:30]1[CH:31]=[CH:32][C:27]([C:4]([C:6]2[N:7]=[CH:8][N:9]([C:11]3[CH:12]=[C:13]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=4[O:23][CH3:24])[CH:14]=[CH:15][CH:16]=3)[CH:10]=2)=[O:5])=[CH:28][CH:29]=1Participants
3
Procedure
This compound is prepared by method C using compound 12c and 1-bromo-4-fluorobenzene
Workup
- customThis compound is prepared by method C
Sources & evidence
- ORD record
- ord-96a35e48800f498e8084310703eebf86