Hydrochloric Acid → 1-methyl-1H-1,2,3-triazole-4-carboxylic acid
Reaction equation
[CH3:1][N:2]1[CH:6]=[C:5]([C:7]([O:9]CC)=[O:8])[N:4]=[N:3]1.[OH-].[Na+].Cl>CO>[CH3:1][N:2]1[CH:6]=[C:5]([C:7]([OH:9])=[O:8])[N:4]=[N:3]1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Using ethyl 1-methyl-1H-1,2,3-triazole-4-carboxylate (1.48 g, 9.54 mmol), methanol (22 mL), 1N sodium hydroxide (15 mL) and 1N hydrochloric acid (15 mL) as starting materials and in the same manner as in Reference Example 12, the title compound (605 mg, 50%) was obtained as a white powder.
Sources & evidence
- ORD record
- ord-22b73dce74e04a03a2a009ad27dea8de
- Source dataset
- uspto-grants-2011_10
- Patent number
- US08044049B2
Reaction notes
Loading…