Dichloromethane → N-[1-[2-[tert-butyl(dimethyl)silyl]oxyethyl]pyrazol-3-yl]-3-cyclopentyl-2-(3,4-dichlorophenyl)propanamide

HRID 166851

Reaction equation

HRID 166851 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH2:8][n:9]1[n:10][c:11]([NH2:14])[cH:12][cH:13]1)([CH3:15])[CH3:16].[CH2:43]([Cl:44])[Cl:45].[CH:25]1([CH2:30][CH:31]([C:32](=[O:33])[Cl:34])[c:35]2[cH:36][c:37]([Cl:42])[c:38]([Cl:41])[cH:39][cH:40]2)[CH2:26][CH2:27][CH2:28][CH2:29]1.[n:17]1[c:18]([CH3:19])[cH:20][cH:21][cH:22][c:23]1[CH3:24]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH2:8][n:9]1[n:10][c:11]([NH:14][C:32]([CH:31]([CH2:30][CH:25]2[CH2:26][CH2:27][CH2:28][CH2:29]2)[c:35]2[cH:36][c:37]([Cl:42])[c:38]([Cl:41])[cH:39][cH:40]2)=[O:33])[cH:12][cH:13]1)([CH3:15])[CH3:16]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 79372,6-LutidineHCID 593449471-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1H-pyrazol-3-ylamineHCID 873027773-Cyclopentyl-2-(3,4-dichlorophenyl)propanoyl chloride

Product 1

HCID 67188510N-[1-[2-[tert-butyl(dimethyl)silyl]oxyethyl]pyrazol-3-yl]-3-cyclopentyl-2-(3,4-dichlorophenyl)propanamide

Sources & evidence

ORD record
ord-df59a5f6f47b4a5cb2687cd8514f6246
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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