Dichloromethane → 3-Methanesulfonyloxy-1-(4-morpholinocarbonyl-1,3-oxazol-2-yl)azetidine

Reaction equation

[CH2:31]([Cl:32])[Cl:33].[CH3:19][S:20]([Cl:21])(=[O:22])=[O:23].[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[OH:1][CH:2]1[CH2:3][N:4]([c:6]2[o:7][cH:8][c:9]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[n:10]2)[CH2:5]1>>[O:1]([CH:2]1[CH2:3][N:4]([c:6]2[o:7][cH:8][c:9]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[n:10]2)[CH2:5]1)[S:20]([CH3:19])(=[O:22])=[O:23]

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 8471Triethylamine

HCID 31297Methanesulfonyl chloride

HCID 222429883-Hydroxy-1-(4-morpholinocarbonyl-1,3-oxazol-2-yl)azetidine

Product 1

HCID 222427343-Methanesulfonyloxy-1-(4-morpholinocarbonyl-1,3-oxazol-2-yl)azetidine

Sources & evidence

ORD record: ord-603136fab5ee4478860da4144395fb12
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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