Hydrochloric Acid → Diethylaminoethylaniline dihydrochloride
Reaction equation
[CH2:1]([N:3]([CH2:6][CH2:7][NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH2:4][CH3:5])[CH3:2].[ClH:15]>CO.O1CCOCC1>[ClH:15].[ClH:15].[CH2:1]([N:3]([CH2:6][CH2:7][NH:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)[CH2:4][CH3:5])[CH3:2]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
To a round bottom flask, 62.6 mg (0.153 mmol) of 5 was dissolved in 1 mL of methanol. To this solution 1 mL of 4 N HCl in dioxane was added slowly, stirred at room temperature for 1 h and concentrated to afford a quantitative amount (52.7 mg) of 6.
Workup
- concentrationconcentrated
Sources & evidence
- ORD record
- ord-82f9d4801e924a9eb76a9a08a30de5b8
- Source dataset
- uspto-grants-2011_08
- Patent number
- US07994172B2
Reaction notes
Loading…