Tert-butyl 2-(benzamido)-4-(3-chlorophenyl)benzoate → 2-(Benzamido)-4-(3-chlorophenyl)benzoic acid
Reaction equation
[C:1]([NH:9][C:10]1[CH:22]=[C:21]([C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([Cl:29])[CH:24]=2)[CH:20]=[CH:19][C:11]=1[C:12]([O:14]C(C)(C)C)=[O:13])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>FC(F)(F)C(O)=O>[C:1]([NH:9][C:10]1[CH:22]=[C:21]([C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([Cl:29])[CH:24]=2)[CH:20]=[CH:19][C:11]=1[C:12]([OH:14])=[O:13])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
10 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(benzamido)-4-(3-chlorophenyl)benzoate and stirred at room temperature for 1 hour. The solvent was evaporated under reduced pressure and methanol was added to the obtained residue and a solid substance was separated by filtration to obtain 21 mg of 2-(benzamido)-4-(3-chlorophenyl)benzoic acid as white solid.
Workup
- customThe solvent was evaporated under reduced pressure and methanol