Aniline → N4-(6-aminopyridin-2-yl)-N6-phenylpyrimidine-4,6-diamine

HRID 167449

Reaction equation

HRID 167449 reaction equation
[C:8](=[O:9])([O-:10])[O-:11].[Cl:14][c:15]1[cH:16][c:17]([NH:21][c:22]2[n:23][c:24]([NH2:28])[cH:25][cH:26][cH:27]2)[n:18][cH:19][n:20]1.[Cs+:12].[Cs+:13].[NH2:1][c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1.[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:15]1[cH:16][c:17]([NH:21][c:22]2[n:23][c:24]([NH2:28])[cH:25][cH:26][cH:27]2)[n:18][cH:19][n:20]1

Participants

6

Reactant 5

HCID 6115AnilineHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 57708264N2-(6-chloropyrimidin-4-yl)pyridine-2,6-diamine

Product 1

HCID 57708273N4-(6-aminopyridin-2-yl)-N6-phenylpyrimidine-4,6-diamine

Sources & evidence

ORD record
ord-a31d415d9a814edca5f1ea254ef3f656
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

Loading…