Ethylamine → Ethyl-isoxazol-5-ylmethyl-amine
Reaction equation
Br[CH2:2][C:3]1[O:7][N:6]=[CH:5][CH:4]=1.[CH2:8]([NH2:10])[CH3:9]>C1COCC1>[CH2:8]([NH:10][CH2:2][C:3]1[O:7][N:6]=[CH:5][CH:4]=1)[CH3:9]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
prepared by reaction of the 5-bromomethyl-isoxazole (Deshong P. et al J. Org. Chem. 1988, 53, 7, 1356-1364) with 2M ethylamine in THF.
Sources & evidence
- ORD record
- ord-9a5dc3ff08a249f481502063fe8c4566
- Source dataset
- uspto-grants-2011_08
- Patent number
- US08003654B2
Reaction notes
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