Methylamine → HCID 12876310, compound
Reaction equation
[CH3:1][C:2]1([C:15]([O:17]C)=O)[C:7]2[NH:8][C:9]3[C:14]([C:6]=2[CH2:5][CH2:4][NH:3]1)=[CH:13][CH:12]=[CH:11][CH:10]=3.[CH3:19][NH2:20]>C(O)C>[CH3:1][C:2]1([C:15]([NH:20][CH3:19])=[O:17])[C:7]2[NH:8][C:9]3[C:14]([C:6]=2[CH2:5][CH2:4][NH:3]1)=[CH:13][CH:12]=[CH:11][CH:10]=3Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
4.8 g (0.02 mol) of methyl 1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate are dissolved in 100 ml of ethanol saturated with methylamine. The solution is left at ambient temperature for 48 hours. The solvent is removed and the residue is then taken up in 20 ml of ethanol. The product is filtered off and washed with ethanol.
Workup
- customThe solvent is removed
- filtrationThe product is filtered off
- washwashed with ethanol
Sources & evidence
- ORD record
- ord-06199cb348db45458e575e60b24f2ae9
- Source dataset
- uspto-grants-1981_06
- Patent number
- US04272539
Reaction notes
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