Hydrochloric Acid → 2-Methyl-9-(2-morpholinoethyl)-3-(4-chlorobenzoyl)imidazo[1,2-a]benzimidazole dihydrochloride
Reaction equation
[CH3:1][C:2]1[N:3]=[C:4]2[N:8]([C:9]=1[C:10](=[O:18])[C:11]1[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=1)[C:7]1[CH:19]=[CH:20][CH:21]=[CH:22][C:6]=1[N:5]2[CH2:23][CH2:24][N:25]1[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1.[ClH:31]>CC(C)=O>[ClH:17].[ClH:31].[CH3:1][C:2]1[N:3]=[C:4]2[N:8]([C:9]=1[C:10](=[O:18])[C:11]1[CH:12]=[CH:13][C:14]([Cl:17])=[CH:15][CH:16]=1)[C:7]1[CH:19]=[CH:20][CH:21]=[CH:22][C:6]=1[N:5]2[CH2:23][CH2:24][N:25]1[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1Participants
4
Procedure
1.7 g of the base obtained in Step B is dissolved in 30 ml of acetone and acidified with concentrated hydrochloric acid: the title compound precipitate is removed by filtration and recrystallised from ethanol.