Dichloromethane → 4-tert-Butoxycarbonyl-1-[(6-chloronaphthalen-2-yl)sulfonyl]-2-ethoxycarbonylpiperazine

HRID 169133

Reaction equation

HRID 169133 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[NH:11][CH2:12][CH2:13]1.[CH:34]([N:35]([CH:36]([CH3:37])[CH3:38])[CH2:39][CH3:40])([CH3:41])[CH3:42].[Cl:19][c:20]1[cH:21][c:22]2[cH:23][cH:24][c:25]([S:30](=[O:31])(=[O:32])[Cl:33])[cH:26][c:27]2[cH:28][cH:29]1.[Cl:43][CH2:44][Cl:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[N:11]([S:30]([c:25]2[cH:24][cH:23][c:22]3[cH:21][c:20]([Cl:19])[cH:29][cH:28][c:27]3[cH:26]2)(=[O:31])=[O:32])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 106351296-Chloronaphthalene-2-sulfonyl chlorideHCID 114026711-tert-Butyl 3-ethyl piperazine-1,3-dicarboxylate

Product 1

HCID 697002244-tert-Butoxycarbonyl-1-[(6-chloronaphthalen-2-yl)sulfonyl]-2-ethoxycarbonylpiperazine

Sources & evidence

ORD record
ord-1d409a04d54c488ca64e014cc79c90bc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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