Tert-Butylamine → 4-bromo-N-(1,1-dimethylethyl)-2-methyl-benzamide

HRID 1695162

Reaction equation

[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([CH3:11])[CH:3]=1.[C:12]([NH2:16])([CH3:15])([CH3:14])[CH3:13]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:16][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:8])=[C:4]([CH3:11])[CH:3]=1

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 995704-Bromo-2-methylbenzoic acid

Product 1

HCID 472997704-bromo-N-(1,1-dimethylethyl)-2-methyl-benzamide

Procedure

The sub-title compound was prepared by the method of example 18 step a) using 4-bromo-2-methylbenzoic acid and tertiarybutylamine.

Sources & evidence

ORD record: ord-2760205b7e6e4e5fb44aa69a284c0e03
Source dataset: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08163727B2

Linked notes

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